Prominently, we observed persistently elevated levels of eotaxin/CCL11, CCL2, CCL7, CXCL1, CXCL10 and BAFF in the DIPG, ALL, and aggressive osteosarcoma models (Figure 2A–2C), the same three models that also exhibit cognitive deficits (Figure 1). This evidence concerns the gene CCL11 and Cognitive impairment.