LHB and concussion: Previous works from our laboratories have established that LHb hyperactivity plays a causal role in motivational deficits in self-care behaviors in a repetitive closed head mTBI model39 as well as this model induces social anhedonia 40 in male mice suggesting that this preclinical model of mTBI may predict some aspects of mTBI-induced reward/motivational circuit dysfunction underlying long-term negative mood outcomes related to mTBI in humans.