With respect to risk factors for poor RFS, rs16944 A/A genotype (p = .03), Child‐Pugh B (p < .01), AFP level (p < .01), DCP level (p < .01), multiple tumors (p < .01), tumor size (p < .01), operation time (p = .03), blood loss (p < .01), number of CTCs (p < .01), and mPVI (p < .01) were predictive factors in the univariate analysis. Here, AFP is linked to neoplasm.