IRGQ and Alzheimer disease: Notably, 5 of these proteins — platelet-activating factor acetylhydrolase Isoform 1B subunit 3 (PA1B3), testican-3 (TICN3), intercellular adhesion molecule 1 (ICAM1), immunity-related GTPase Q (IRGQ), and aldehyde dehydrogenase 1 family member L1 (AL1L1) — were uniquely associated with RAD, suggesting their potential significance in the pathogenesis of AD.