The expression levels of PI3K were seen in some areas of tumor tissue in treatment group-I (15 mg/kg), with diffuse, moderate cytoplasmic positivity (Fig. 9E), the expression levels of NF-kB are weak to moderate cytoplasmic and nuclear expression is seen in some areas (Fig. 9H), and the expression levels of COX-2 were seen in areas with scattered tumor cells show weak to moderate cytoplasmic expression (Fig. 9K). Here, PTGS2 is linked to neoplasm.