Mesenchymal stem cells derived from adipose tissue (ADSCs) when treated with exosomes derived from two ovarian cancer cells (OVCAR-3 and SK-OV-3) show distinctive features of tumor-linked myofibroblasts as characterized by elevated expression of α-smooth muscle actin, TGF-β, stromal derived factor-1 (SDF-1), and TGF-β receptor I and II. This evidence concerns the gene TGFB1 and ovarian carcinoma.