Expression of TGFβ1, melanoma antigen (MAGE) 3, and 6 is upregulated in ovarian cancer derived-exosomes compared with that in exosomes derived from benign ovarian lesions (serous cysts) or normal cells suggesting that these proteins could be biomarkers to distinguish malignant and benign tumors [87]. The gene discussed is TGFB1; the disease is ovarian carcinoma.