The qPCR results in human colon carcinoma cell line HCT116 and uveal melanoma cell line MP41 showed the identical trend (Fig. S1B, C) These results indicate that TH1579 treatment broadly increases PDL1 gene expression across a range of tumour types, potentially enhancing the responsiveness of these cells to anti-PD-L1 antibody therapy. The gene discussed is CD274; the disease is colon carcinoma.