Currently, some authors demonstrate that butyrate interferes with cellular signaling involving the pro-inflammatory transcription factor NF-κB and the antioxidant transcription factor Nrf2 as a mechanism of action to attenuate allergic asthma [66] and the secretion of pro-inflammatory mediators from epithelial cells after exposure to LPS [67]. Here, NFE2L2 is linked to allergic asthma.