It is worth noting that the mentioned alteration may be a consequence of the enhanced pAkt level and may provoke the promotion of nuclear factor erythroid 2-related factor 2 (Nrf-2) response, protecting the inflammation development from HFD-induced steatosis and its progression to hepatitis [45], which was also noticed in our previously published data [19]. This evidence concerns the gene NFE2L2 and steatosis.