The reduction in tumour weight seems to be explained, among other mechanisms, by the results in the study showing that tumour cell proliferation was arrested in phase S. The apoptosis test (Annexin V-FITC/PI) showed that tumour apoptotic cells increased from 6% (control) to 76% (highest DVA dose), whereas normal sarcoma cells went down from 91% (control) to 19%. The gene discussed is ANXA5; the disease is neoplasm.