It activates COX-2 and controls the synthesis of many proinflammatory cytokines (IL-1β, IL-6, TNF-α, and INF-gamma), which are essential in the development of asthma, COPD (chronic obstructive pulmonary disease), and autoimmune diseases (like multiple sclerosis, rheumatoid arthritis, and Crohn’s disease) as well as cardiovascular conditions like atherosclerosis [121,122,123]. The gene discussed is IL1B; the disease is chronic obstructive pulmonary disease.