FGF2 and hepatocellular carcinoma: Previously, Lin et al. [7] showed that the recombinant polypeptide of HGFK1 (rHGFK1) inhibited the basic fibroblast growth factor (bFGF)-induced proliferation of bovine aortic endothelial cells and suppressed tumor growth and metastasis by inhibiting tumor neovascularization in an established rat orthotopic hepatocellular carcinoma (HCC) model.