In this randomized study, the authors found a beneficial effect at the biochemical level—an increase in collagen and elastin concentrations—at the histological level—a thickening of the vaginal epithelium—and at the clinical level—an improvement in the symptoms of urogenital atrophy, which was assessed by the VHI (Vaginal Health Index) and the ICIQ UI SF (International Consultation on Incontinence Questionnaire Urinary Short Form), evaluating stress urinary incontinence. This evidence concerns the gene ELN and Stress urinary incontinence.