It can also diminish PCNA, CD68, CD3, monocyte chemoattractant protein-1 staining, cytokine-induced neutrophil chemoattractant-1 and the level of the marker of DNA damage, and 8-oxo-7,8-dihydro-2′-deoxyguanine in RA rats [331]. The gene discussed is CCL2; the disease is rheumatoid arthritis.