Among non-hematological toxicities, the most frequent AE was nausea and vomiting (66.7%), followed by hair loss (54.2%), fatigue (36.1%), diarrhea (18.1%), abnormal renal function (18.1%), increased ALT (16.7%), skin rashes (16.7%), increased AST (15.3%), stomatitis (13.9%), and constipation (2.8%). This evidence concerns the gene GPT and Skin rash.