CD4 and COVID-19: With respect to the effect size, however, CD39+CD45+ cells appeared to be a stronger predictor for COVID-19 severity as compared with TIM3+CD39+CD4+CD3+CD45+ lymphocytes, as indicated by an OR of 51.4 (95% CI 1.5 to 173) versus an OR of 22.6 (95% CI 1.8 to 277).