CD8A and dengue disease: To determine which of these experimentally validated globally reported dengue-specific CD4 and CD8 T cell epitopes are conserved among the dengue viruses circulating in India, we first curated a total of 107 published complete polyprotein sequences of dengue viral isolates reported from India, beginning in 2005 (when a major dengue outbreak occurred) and continuing to the date of this analysis, as outlined in the methods section.