Pathways associated with bone development and disease included the Role of Osteoblasts in Rheumatoid Arthritis Signaling; the Role of Osteoblasts, Osteoclasts, and Chondrocytes in RA (Figures S4 and S5); Chondroitin Sulfate Biosynthesis; and RANK Signaling in Osteoclasts. This evidence concerns the gene TNFRSF11A and rheumatoid arthritis.