Several urinary biomarkers were reported as PCa biomarkers, including Engrailed 2 protein, sarcosine, alpha-methyl CoA-racemase (AMACR), and the prostate cancer gene 3 (PCA3), a long noncoding RNA (lncRNA) exclusively produced in prostate cancer tissues [7]. The gene discussed is PCA3; the disease is Familial prostate cancer.