The most common genes are the ones which are implicated in the sodium and potassium channels: SCN5A (BrS), KCNQ1 (LQTS), KCNH2 (LQTS), KCNE1 (LQTS) for conditions like LQTS and BrS; additionally, for the CPVT, the most frequent gene is RYR2. The gene discussed is KCNE1; the disease is familial long QT syndrome.