In addition to nuclear features, specific histological features have been described for these leiomyomas, including dilated staghorn vessels, perinuclear halos, and eosinophilic cytoplasmic inclusions, which are quite specific to leiomyoma with FH deficiency [2,9], similar to that observed in our cases. The gene discussed is FH; the disease is hyperinsulinemic hypoglycemia, familial, 4.