Nagel et al. recently outlined through RNA sequencing gene expression data that in contrast with ALK+ ALCL cell lines, BIA-ALCL cells show high expression of BLC2 and cyclin D2 (CCND2), the latter being a key cell cycle regulator through its activity on CDK4 and CDK6 [51]. The gene discussed is CCND2; the disease is anaplastic large cell lymphoma.