Furthermore, in TCGA tumors with paracancerous tissue as controls (Figure 1C), upregulation of GJA1 expression was found in four tumor types, including CHOL, HNSC, KIRC, and LICH, and downregulation of GJA1 expression was found in KICH, LUAD, PRAD, and THCA. Here, GJA1 is linked to neoplasm.