CXCL11 and colonic neoplasm: For example, it has been reported that the expression of chemokine ligand C-X-C motif chemokine ligand 11 (CXCL11) was upregulated in colon cancer tissue compared to normal tissue, and that tumor patients with high CXCL11 expression have a better prognosis, which may be associated with lower tumor-promoting immune cells and higher anti-tumor immune cells in the group with high CXCL11 expression [56].