Among all the therapeutic aspects approached by the scientists and clinicians fighting against cancer, the aspects concerning tumour cell proliferation, tumour growth, the immuno-histological particularities related to ki67 (originally marker of proliferation Kiel 67, sometimes named MKI67) expression and the malignant cellular mitotic rate play an important role in the aggressiveness assessment and aggressiveness prognosis. This evidence concerns the gene MKI67 and neoplasm.