While our study did not find a significant association between the LAG3 rs12313899 polymorphism and AML risk, a few other studies have reported associations between LAG3 genetic variations and susceptibility to or prognosis of some cancer types, including AML [23], where LAG3 rs2365094 was associated with risk stratification for AML in a Chinese population from Ji’nan, Shandong. Here, LAG3 is linked to acute myeloid leukemia.