In a very recently published study, Yao et al. [37] assessed the predictive role of AFP in patients undergoing liver resection of early-stage HCC and showed that patients with high (400–999 ng/mL) and extremely high (≥1000 ng/mL) preoperative AFP were characterized by worse OS compared with patients with low (<400 ng/mL) AFP. Here, AFP is linked to hepatocellular carcinoma.