SLC9A3 and adenoma: The exchangers SLC9A3 (solute carrier family 9 member A3), also known as sodium-hydrogen exchanger 3 (NHE3), and SLC26A3 (solute carrier family 26 member 3), known as down-regulated in adenoma (DRA), are key ion transporters in the apical region of epithelial cells of the lower gastrointestinal tract [126,127].