Leucovorin (folinic acid) 25 mg QD, along with 15 mg of l-methylfolate (Folafy ER, Xymogen), was added to help counteract the dapsone-induced anemia, and N-acetylcysteine 600 mg twice a day, 600 mg of alpha lipoic acid, and 500 mg of liposomal glutathione were continued to support a healthy inflammatory pathway and help lower methemoglobin levels. Here, HBG2 is linked to anemia (phenotype).