MMP2 and colorectal cancer: A second point of interest analyzed in the present study consisted of the investigation of ASA in different concentrations (1, 2.5, 5, and 7.5 mM, for 72 h) and its impact on human colorectal cancer cells (HCT-116), looking at cell viability percentage, cellular morphology changes, migratory capacity, cytoskeleton and nuclear alterations, and the expression of matrix metalloproteinases -2 and -9.