INS and type 2 diabetes mellitus: A previously published meta-analysis demonstrated benefits of a combination of a GLP-1RA and a basal insulin over a basal-bolus insulin (BBI) regimen in patients with type 2 diabetes in the form of a (non-significant) improvement in glycated hemoglobin (HbA1c), concomitant weight reduction, and lower relative risk of hypoglycaemia [6].