HERC6 and systemic lupus erythematosus: In the comparison, multiple genes with relatively considerable elevations in common for both groups (i.e., Wald-test statistics > 6.0), where many of these were overlapping with those from the comparison with the SLE, were demonstrated: (i) innate immunity: Ifih1, Ifit2, Ifitm3, Oas3, Parp9, Stat1, Stat2, Herc6, Parp14, Parp9, Znfx1, Casp1, and Tap1; (ii) adaptive immunity: Tap1 and Socs1; and (iii) mitochondrial innate immunity: Casp1, Ifih1, and Znfx1, (iv) RAAS: Mlkl, (v) ISR: Glrx and Txn1.