The median CRP and LRG values in the normal-mucosa group were significantly lower than those of the IBD and other IBD-colitis groups, respectively, as follows: CRP, 0.03 mg/dL vs. 0.17–0.45 mg/dL, p < 0.01; LRG, 9.5 μg/mL vs. 13.6–22.1 μg/mL, p < 0.01. This evidence concerns the gene CRP and irritable bowel syndrome.