Comorbidities in the non-endometriosis control group were diabetes and insulin sensitivity in 5/62 (8%), constipation/IBS 9/62 (15%), and PCOS, fibroids, simple ovarian cysts, inflammatory bowel disease, collagen vascular disease, interstitial cystitis in the 2–5/62 or 3–8% range. Here, INS is linked to irritable bowel syndrome.