Moreover, although an effort was made in order to optimize Crohn’s disease patients’ metabolic condition prior to surgery, patients in this group had significantly poorer nutritional status (as measured by albumin levels as well as BMI), and a significant number of them were receiving steroid treatment in the pre-operative period—all of which are known risk factors associated with a higher leak rate [4,7,9,10,12,15,16,17,20]. The gene discussed is ALB; the disease is Crohn disease.