The conclusions of previous studies were that (a) CRP did not accurately predict severe infection or sepsis in children with a severe burn [8]; (b) CRP accurately predicted mortality in severe burns [8,9]; (c) CRP had a better predictive potential in an elderly group with severe burns [9]; (d) CRP was correlated with the systemic inflammatory response [8,9,12]; (e) CRP was correlated with gender, race, age, and other factors [13]. The gene discussed is CRP; the disease is infection.