FOXO4 in OSA tissue had a 1.42 Log2 fold decrease, but not significant at p = 0.056, compared to patient-matched non-tumour bone; IRF8 showed a 2.33 Log2 fold decrease, p = 0.01, and LEF1 exhibited a 2.2 Log2 fold increase, p = 0.04. This evidence concerns the gene LEF1 and neoplasm.