The upregulation of E-cadherin (epithelial marker); downregulation of Snail (EMT-TF, and downstream gene of mTOR), Vimentin, and N-cadherin (mesenchymal markers); and reduction of migration capacity successfully validates the suppressive role of miR-99b-5p in regulating EMT and EMT-mediated metastasis in PCa. The gene discussed is CDH2; the disease is posterior cortical atrophy.