CD274 and hepatocellular carcinoma: Overexpression of PD-L1 in HCC histology has been associated with poor prognosis in a series of 217 HCC patients, but the IMBrave150 trial revealed thatPD-L1 expression predicted a good outcome in patient treated vit atezolizumab/bevacizumab compared with patients treated with sorafenib [20,21].