Accumulation of VCAN in peritumoural stroma was associated with the prognosis of node-negative breast cancer [142], early stage prostate cancer [143], NSCLC [144], oral squamous cell carcinoma [145], testicular germ cell tumours [146], cervical cancer [147], endometrial cancer [148], and epithelial ovarian cancer [149]. This evidence concerns the gene VCAN and childhood testicular germ cell tumor.