The cellular localization patterns of the KEAP1 and NRF2 proteins were investigated in N417 (with no alterations in KEAP1 and NFE2L2), H69V (KEAP1-methylated), and H1184 (with the KEAP1 p.Gly364Cys mutation) SCLC cell lines via immunofluorescence analysis. The gene discussed is NFE2L2; the disease is small cell lung carcinoma.