For WAs, a combination of three lncRNAs (RMRP, H19, and NEAT1) along with smoking pack-years achieved an AUC of 0.87, enabling the diagnosis of NSCLC with 83% sensitivity and 79% specificity, and 81% accuracy (all p < 0.05) (Figure 1C). This evidence concerns the gene H19 and non-small cell lung carcinoma.