The differential diagnosis between the EVT and ChrRCC is easier to make, in that it relies on all the previous markers plus CK7, which is typically, diffusely, and strongly expressed in ChrRCC; furthermore, the latter tumor lacks prominent cytoplasmic vacuoles and striking nucleoli, whereas the EVT does not feature typical ChrRCC raisinoid nuclei with perinuclear halos [28,31]. The gene discussed is KRT7; the disease is neoplasm.