While cyclophosphamide combined with granulocyte-colony stimulating factors (G-CSF) is frequently used as mobilization therapy in many institutions, Swiss centers alternatively use vinorelbine + G-CSF or gemcitabine + G-CSF, which have both been shown to be safe and effective [20,42,43,44], with gemcitabine being preferentially used in patients with pre-existing polyneuropathy [20]. Here, CSF3 is linked to polyneuropathy.