STK11 and neoplasm: The authors, after identifying KL-specific downregulation of genes involved in dsDNA sensing—especially TMEM173/STING, which was also reduced in LKB1-mutant KRAS wild-type NSCLC cell lines—performed IHC to validate their findings and analyzed tumor cell-specific STING protein levels across a panel of 64 patient-derived NSCLC samples enriched for KRAS-mutated status.