CDH2 and gastric cancer: Furthermore, PGC inhibited the migratory and invasive ability of GC cells and downregulated mesenchymal cell markers (N-cadherin, vimentin, and fibronectin), metalloproteinases (MMP-2, MMP-9), and other metastasis-related proteins (Snail, Slug, Twist), and it upregulated epithelial cell marker (E-cadherin) expression, thereby inhibiting the EMT progression of GC cells.