Regarding the acute inflammatory death of adult zebrafish by CML toxicity, a co-injection of apoA-I+CIGB-258 induced the highest survivability, lowest hepatic hyperinflammation, and lowest IL-6 levels (Figure 8, Figure 9, Figure 10 and Figure 11). This evidence concerns the gene APOA1 and chronic myelogenous leukemia, BCR-ABL1 positive.