In the presence of CML to induce the acute death of zebrafish embryos, a co-injection of an apoA-I:CIGB-258 mixture helped induce higher survivability and faster developmental speed with lower apoptosis and ROS production according to the CIGB-258 content (Figure 6 and Figure 7). The gene discussed is APOA1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.