PFN1 and obstructive sleep apnea syndrome: Based on bioinformatical analysis, 13 candidate genes that are potentially deregulated in WCB cells upon maternal OSA were selected from the gene list previously identified in the five biological processes, including 12 upregulated mRNAs (PFN1, UBA52, EGR1, STX4, MYC, JUNB, MAPKAP1, IGF2, CAT, MCL1, PPP1CB and AKT2) and 1 downregulated mRNA (PRKAR1A) (Figure 5).