CPN1 and cancer: Well-documented scientific evidence is reported for some of them for their involvement in cancer (NORAD, SNHG6, NFS1, SLMO2-ATP5E, RAB5IF, EDEM2, VAPB, RBM39, TPD522, CPN1, SRSF6), and they gave us good confidence in the validity of the model adopted, suggesting the necessity of further analysis to investigate their involvement in the mechanisms supporting CRC pathogenesis.