SOCS3 and infection: In the present study, we observed an increase in the relative expression of IL-10 and SOCS3 in the pre- and post-infection assays with B. longum and C. sorokiniana as compared with rotavirus-infected cells without treatments, which may indicate that the protective effect of this probiotic and the microalga was also induced by IL-10 and SOCS3 by downregulating a pro-inflammatory response in rotavirus-infected cells.