VEGFA and Headache: Other parameters characterizing migraine include the following: pain intensity evaluated by numeric rating scale (NRS), the number of headache attacks per month or quarter, duration of migraine, occurrence of aura, number of attacks per month, the use of gepants, triptans, onabotulinumtoxinA, and non-steroidal anti-inflammatory drugs in the abortive treatment and the use of anti-VEGF drugs, and other drugs in preventive treatment were not correlated with TRP metabolism.